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Sanofi did combine lixisenatide with insulin glargine in a premixed pen (Soliqua), which was a novel combo product for patients needing both basal insulin and a GLP-1 RA

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3,19,20 They stimulate satiety , the sense of feeling full after a meal, reducing cravings and caloric intake.GLP-1 agonists are approved for use in some people with type II diabetes, and two of them are FDA-approved for weight loss in certain people and situations