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A well-characterized example is ezatiostat (TLK199)a GSH peptidomimetic moleculedesigned to display enhanced cellular uptake and whose metabolites bind the G-site of GSTP1-1 causing enzyme inhibition

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2010 Apr 22;1(1-2):823

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Rapid, severe hair loss that exceeds what would be expected for telogen effluvium, losing large clumps rather than diffuse thinning, warrants urgent evaluation

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However, the FDA still must review the actual application and determine whether the statutory and regulatory requirements for licensure are satisfied

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We take a whole-person approach and stay on the leading edge of what works

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