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Common side effects may include allergic reactions, gastrointestinal discomfort, and potential interactions with medications
A phase 2 trial assessing mazdutide 3, 4.5 and 6 mg in a Chinese population with overweight/obesity demonstrates up to 11.3% WL after 24 weeks of treatment compared to 1% weight gain with placebo [70]
This study utilized a randomized, placebo-controlled, double-blind, multicenter study design, a full 10-week supplementation, blood monitoring at baseline and posttreatment, and multiple assessments of various functions
However, oral peptide supplements are becoming more available for at-home use
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