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Semaglutide 2.4 mg (Wegovy, FDA-approved for weight management) reports diarrhea in approximately 30% of patients in clinical trials according to the FDA prescribing information

Cukierman-Yaffe T, Gerstein HC, Colhoun HM, Diaz R, Garca-Prez LE, Lakshmanan M, Bethel A, Xavier D, Probstfield J, Riddle MC

As illustrated in Figure 1, this review comprehensively analyzes the mechanistic basis of GLP-1RAs in ocular diseases, synthesizes emerging clinical and preclinical evidence, and underscores their potential to redefine therapeutic strategies for vision-threatening disorders through multi-targeted disease modification

These findings suggested that MT2 might trigger sexual arousal centrally (via the brain), not just as a side effect of a vascular mechanism