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Six enzymes of folic acid metabolism pathway were overexpressed, among which serine hydroxymethyltransferase 1 promoted the expression of cancer inflammatory factors by regulating sialic acid N-acetylneuraminic acid, and promoted the growth and metastasis of ovarian cancer tumor cells (69)

Ying J, Xu X, Zhou R, Chung AC, Ng SK, Fan X, Subramaniam M, Wong SH (2025) The gut microbiota in young adults with high-functioning autism spectrum disorder and its performance as diagnostic biomarkers

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Activation of these receptors may modulate dopamine signaling, potentially reducing alcohol's rewarding properties, though the exact mechanisms in humans remain under investigation