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Table A : GLP-1RAs versus other glucose-lowering agents: key specific features that impact treatment choice Given that there are few head-to-head studies comparing glucose-lowering effects between different drug classes, and the difficulty involved in performing cross-study comparisons due to different patient characteristics and baseline HbA 1c levels, there is widespread consensus that GLP-1RAs are more efficacious at lowering blood glucose than either DPP-IVs or SGLT-2 inhibitors
Moreover, the study found notable differences in the C6:0/C10:0 ratio between individuals with HGDA and CRC patients (1.48 and 0.13, respectively)
However, preliminary studies in non-diabetic obese individuals showed that simultaneous activation of GLP-1 and GIP receptors did not potentiate GLP-1-mediated effects in lowering food intake and appetite (79)
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