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Developed in the 1980s at the University of Arizona, this peptide was originally designed to stimulate melanogenesis for skin pigmentation but was subsequently found to produce significant effects on sexual function, appetite regulation, and social behavior
Pharmacology Mechanism of Action Semaglutide is a GLP-1 analogue with 94% sequence homology to human GLP-1
At the same time, GLP-1s anti-inflammatory effects argue against a simple pro-ischemic mechanism
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