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Vitamin B12 absorption occurs primarily in the terminal ileum through intrinsic factor-mediated absorption (for both dietary and supplemental B12) and passive diffusion (particularly relevant for high-dose supplements)
Both metformin and long-term use of proton pump inhibitors have been linked to reduced B12, and the same goes for many people past 50
Patients often finish NAD+ treatment reporting positive effects (such as increased energy or mental clarity) with few downsides aside from the transient discomforts noted above
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Shoulder mobility at week 6 was good
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