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However, the side products of the copper redox cycling, particularly hydroxyl radicals produced via the Harber-Weiss reaction, are among the most reactive and damaging forms of reactive oxygen species (ROS) 35

Sexual arousal triggers the release of NO from endothelial cells and nerve endings in the penile tissue

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Hypoglycaemia: Mainly if combined with insulin or sulphonylurea

The high heterogeneity of the results likely responds to different baseline A1c, variable rates of obesity, as well as different titration protocols to adjust insulin doses