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Shanghai Science and Technology Committee (19ZR1467500 to H.M.)

A previous publication from the same population in the aforementioned clinical study found a 49% lower risk of cardiovascular mortality among the supplemented participants during a median follow-up period of 10 years

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Reinitiation Criteria: Clinicians should consider increasing the dose or reinitiating therapy if a patient experiences more than 5% weight regain

2.4 Nontargeted metabolomic assays and analysis S