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In response to oxidative stress, this regulatory mechanism allows NRF2 to rapidly translocate to the nucleus and activate transcription of antioxidant and phase II detoxifying enzymes to effectively mitigate external insults (Figure 2)

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Rotate application sites : Do not apply consecutive patches to exactly the same location

Melissa Jones, 19, from Chester, says she has seen way more people of colour including south-east Asian girls like me getting into tanning