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The condition significantly impacts quality of life and can be triggered or worsened by various factors including diet, stress, and certain medications
Patients should ask whether they are medically appropriate candidates, which medication option fits their history, what side effects to watch for, how labs will be monitored, how the dose will be adjusted, and how muscle mass will be protected
Adjuvant properties are mainly provided by DAMPs, including ATP, HMGB1, CRT, HSPs and so on (82)
Clinical experience suggests that higher-dose formulations approved for weight management (rather than diabetes-only doses) are generally necessary to achieve meaningful weight loss in the post-bariatric population
Some of these effects are reversible upon cessation
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