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Discussion We have conducted the largest real-world retrospective cohort study to date investigating the safety and outcomes of individuals with type 1 diabetes using SGLT2i and GLP-1 RA therapy, and the first to report cardio-renal benefits
Analyses of endpoints for the trial product estimand were not adjusted for multiplicity
J Pers Med 14(7):776 Schaffner M, Mhlberger N, Conrads-Frank A, Qerimi Rushaj V, Sroczynski G, Koukkou E, Heinsbaek Thuesen B, Vlzke H, Oberaigner W, Siebert U (2021) Benefits and harms of a prevention program for iodine deficiency disorders: predictions of the decision-analytic euthyroid model
However, mild side effects may include: Nausea Headache Dizziness Stomach discomfort Consult a healthcare professional if: Symptoms persist or worsen Unusual reactions occur Precautions and Safety Measures Alcohol Avoid alcohol as it may increase side effects Pregnancy & Breastfeeding Use only under medical supervision Driving Avoid driving if dizziness occurs Medical Conditions Use cautiously in liver or kidney disorders Storage Instructions Store in a cool, dry place Keep away from sunlight and moisture Keep out of reach of children Proper storage ensures maximum effectiveness and safety
At the end of 4 years, there were more people alive in the Wegovy group than in the placebo group: So its certainly true that we dont know what happens when you take these drugs for decades
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