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In acute ischemia, excessive astrocyte-derived lactate may also aggravate injury by promoting pathological protein lactylation [13]
Thus, side effects are rare when used properly
Enzyme-linked immunosorbent assay kits were used to determine the levels of pro-inflammatory cytokines, specifically TNF- and IL-6, in cell culture supernatants
Collectively, these factors highlight the need for carefully designed therapies that can selectively target GSH in tumors while minimizing toxicity and overcoming adaptive resistance mechanisms
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