Funding None Availability of data and materials All data supporting the conclusion of this article are included in this published article
And in short that came out a few years after that STEP 1 trial what we did for the very first time is take individuals with obesity and pre-existing cardiovascular disease, like a prior stroke, prior heart attack, or peripheral arterial disease, called PAD, and they're on maximal therapy for their cardiovascular disease or stroke, and then randomized them on top of that to either semaglutide or placebo
As the body adapts and metabolism stabilizes, sleep quality often improves
If diarrhoea is severe, persistent, or continues for several days, it is important to speak to a healthcare professional to review your treatment and make sure you are properly supported
How to prevent injection site reactions Prevention is much easier than treatment