A simplistic approach of holding the GLP-1 RA for longer intervals (3-5 weeks) may not be tenable, especially when prescribed for glycemic control
It is for informational purposes only and does not replace medical care and advice from a healthcare provider
For instance, GLP-1RAs were demonstrated to reduce the risk of cardiovascular events (5) by decreasing the blood pressure (6), improving microvascular function, and reducing inflammation (7)
FIGURE 1 On the surface, the mice after GPX1 KO performed normally, but these mice were susceptible to the production of oxidative substances, and when stimulated, they were easy to cause harm to mice and increase oxidative stress in vivo
Patients who began therapy with GLP-1 receptor agonists were compared with individuals treated with SGLT2 inhibitors (sodium-glucose cotransporter-2 inhibitors) , another widely used class of diabetes medications