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Majeed and colleagues found a notable improvement in the symptoms of depression and IBS in patients treated with Bacillus Coagulans MTCC 5856 (234)
The mechanism (crossing the blood-brain barrier to raise alpha brain waves and gently modulate GABA, glutamate, dopamine and serotonin for relaxation without sedation)
Moderate Evidence Base: Certain oral dietary supplements have published research, though results vary across studies and individuals
Taken together, the observations in patients by MRS studies indeed offer in vivo evidences supporting the presence of glutamatergic, redox and mitochondrial dysfunction in schizophrenia, despite many confounding factors involved such as MR methodologies, disease stage, region specificity, heterogeneity in patient cohorts and medication effects
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