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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for type 2 diabetes management, have demonstrated remarkable efficacy in addressing the multifactorial pathogenesis of MASLD/MASH [7-10]
Stay hydrated before and after injections
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Retatrutide activates three hormone receptors: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors
These thermoregulatory changes are typically temporary and may improve as weight stabilizes and the body adapts to its new composition
