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A recent meta-analysis of all the double-blind, placebo-controlled, randomized clinical trials of N-acetylcysteine as adjunctive therapy in bipolar depression confirmed its superiority over placebo in reducing depressive symptoms with a moderate effect size (95% confidence interval 0.060.84) [61]
A small but significant portion undergoes cytochrome P450 (CYP2E1) oxidation, producing the reactive intermediate N-acetyl-p-benzoquinone imine (NAPQI)
Effect of Telmisartan and Quercetin in 5 Fluorouracil-induced renal toxicity in rats
Flaxseed oil ameliorates alcoholic liver disease via anti-inflammation and modulating gut microbiota in mice
J Clin Oncol:JCO2016714394
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