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Slightly higher doses of CCK-8 administered via intraperitoneal injection (~110 g/kg) activate vagal afferents and increase neuronal activation in the NTS where VANs terminate, while vagotomy and capsaicin treatment abolish the suppressive effects of CCK-8 administration 177,178

The Wegovy SmPC includes precautions regarding pancreatitis, gallbladder disease, risk of dehydration and acute kidney injury, and diabetic retinopathy in people with type 2 diabetes

What to eat on injection day Some users prefer lighter meals on injection day to minimize nausea

No membership fees, and Medicare may help cover the care