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The mechanisms could include reduced inflammation, improved metabolic health, direct effects on brain reward pathways, or the psychological benefit of successful weight management
Central administration of GLP-1 receptor analogues alters CSF flow Considering the abundant systemic targets for peripherally delivered GLP-1R modulators [12, 38,39,40], which could affect brain fluid dynamics indirectly, we determined the effect of delivering the GLP-1R analogues into the lateral ventricle prior to quantification of the CSF flow
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It can be a slow IV push or an IV infusion
