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Cisplatin, a potent antitumor agent widely employed in the chemotherapy of various solid malignancies, is notorious for severe side effects such as nausea, vomiting, cognition loss, neurotoxicity, and neuropathy

In summary: Citicoline supports dopamine and acetylcholine signaling in the prefrontal cortex, helping improve motivation, working memory, and sustained attention

received honoraria as a speaker for AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, Elpen, Galenica, GSK, MSD, Mylan, Novartis, Novo Nordisk, Pfizer, Sanofi Aventis, Takeda and Vianex

FFA2 knockout mice were obtained from Professor McKay at the Garven Institute

If you experience persistent nausea, the dose escalation protocol matters enormously