A referral to dermatology can help determine the cause and manage the flare while you consider alternative B12 strategies
Age alone is a weaker reason than it is usually presented as: whole-blood NAD+ does not reliably fall with age, and the decline that does show up is tissue-specific and load-dependent
Usually the discomfort is short lived and does not linger after a minute
Furthermore, excess homocysteine acts as a severe neurotoxin
If you let it go for too long, it can cause problems in your nervous system such as: Vision problems Memory loss A pricking or numbing sensation Difficulty speaking or walking due to ataxia (loss of physical coordination) Damage to your extremities (hands, feet, arms, etc.), particularly your legs Other problems could include Infertility (this should go away with B12 treatment) Stomach cancer Bleeding and infections Damage your heart, brain, bones, and other organs in your body If you're pregnant and don't get enough vitamin B12, your baby is at risk of a serious birth defect called a neural tube defect