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Hence, because some of the cardiovascular benefits of SGLT2is are related to their hemodynamic effects, while those of GLP-1RAs are mainly related to their anti-atherogenic/anti-inflammatory actions, the two classes of medications may produce an additive cardiovascular benefit [11]
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Sikiric and colleagues have repeatedly characterized it as "stable in human gastric juice," a property attributed to its high proline content and the absence of cleavage-prone residue pairs (Sikiric et al., 2018)
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The majority (73%) of providers do not believe GLP-1 drugs are sustainable beyond 2-3 years, and none think they should be taken for life
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