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Among individual GLP-1 RAs, exenatide exhibited the longest median time to onset at 45 days (IQR = 11213 days), while dulaglutide had the shortest at 7 days (IQR = 29 days), liraglutide at 16 days (IQR = 5.561 days), semaglutide at 12 days (IQR = 445.5 days), and tirzepatide at 10 days (IQR = 235.5 days)
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However, this is unlikely, as Ex4 reduces intravenous self-administration of alcohol in male mice ( per se as an indication of conditioned aversion ( When tentatively treating individuals with alcohol use disorder using GLP-1R agonists, it is important to take into account the potential aversive effects
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