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New England Journal of Medicine, 368(17), 1575-1584 14
In clinical practice, I find that the rate of weight loss correlates reliably with the improvement of insulin sensitivity
(2019) 14:e0221345
When used in combination with a vascular disrupting agent (CA4-NPs) to boost tumor fibrin deposition and intensify hypoxia, this nanodrug achieved remarkable efficacy: a 98.1% inhibition rate in CT26 tumor models (initial volume ~480 mm) and complete eradication of tumors in 4 out of 6 treated subjects after a single dose (288)
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