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What used to be a $1 or $1.5 billion market space is now a $5 or $6 billion market space and it is growing very rapidly because more and more drugs are coming out into the market, which are peptides. Saharsh Davuluri, Vice-Chairman & MD, Neuland Laboratories | Q1 FY26 Its not just about the weight loss drugs that have been commercialized, but its also about the next gens, not just from the large companies, but other companies as well
There is minimal research on how GLP-1 medications affect individuals who take the medication for cosmetic weight loss, with no underlying health conditions
Data from other groups and our recent study have shown that endothelium and cardiac and vascular myocytes express a functional GLP-1R, and participate in the protective cardiovascular effects of GLP-1 analogues 11,36,37,38
The VESPER trials, in plain English Pfizers VESPER program is structured around a practical question: can you get people through the highest-nausea part of GLP-1 therapy with weekly titration, then hold them on a monthly regimen without losing efficacy or tolerability