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Among the GLP-1 analogs, tirzepatide showed the most pronounced decrease in respiratory quotient (RQ) (Fig
it crosses the blood-CSF barrier
In a prospective real-world cohort of 194 adults with type 2 diabetes initiating semaglutide or dulaglutide, only 49% achieved 5% weight loss by 12 months meaning that just under half of treated patients did not meet the threshold conventionally defined as clinically meaningful (Vozza et al., 2025)
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Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
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