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CJC 1295 stimulates growth hormone secretion and will keep a steady increase of Human Growth Hormone (HGH) and IGF-1 leading to fat loss and increase protein synthesis thereby promoting growth
doi: 10.3389/fmars.2021.665576 209 NilssonS
Stopping tirzepatide cold turkey is possible but can cause uncomfortable appetite surges and GI adjustment symptoms
Reductions in body weight were significantly greater with the LY3298176 1.5 mg, 4.5 mg and 10 mg doses versus placebo in MAD HS (LSM difference [95% CI]: -1.75 kg [-3.38, -0.12], -5.09 kg [-6.72, -3.46] and -4.61 kg [-6.21, -3.01], respectively) and doses of 10 mg and 15 mg had a relevant effect in T2DM patients (LSM difference [95% CI]: -2.62 kg [-3.79, -1.45] and -2.07 kg [-3.25, -0.88], respectively
But their off-label use for weight loss pushed them into the headlines
