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Main Contraindications for GLP-1 Agonists GLP-1 agonists are generally well-tolerated, but they're not suitable for everyone
Supervision matters because it screens for the situations where the therapy is not appropriate and keeps dosing matched to your needs
Do not double the next dose to compensate for a missed one
The conservative approach: when escalating doses, preemptively increase hydration by 20-30% for the first 2 weeks at the new dose
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