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Dose-limiting toxicity has not been precisely defined in humans, yet practitioners should terminate infusions if severe dizziness, chest tightness, or abrupt blood-pressure drops occur, then reassess electrolyte status and acid-base balance before re- challenge
Its pharmacological activity depends on the precise amino acid sequence, proper folding, and correct post-translational modifications
JAMA Netw Open 2024;7:e2413172
Non-economic damages: Pain, emotional distress, and loss of enjoyment of normal diet and social life
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