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doi: 10.33549/physiolres.934781 85 Maghsoumi-NorouzabadLZare JavidAMansooriADadfarMSerajianA

Food supplements should not replace a varied and balanced diet and a healthy lifestyle

A recent study on humans and mice demonstrated that disrupted GH signaling was associated with elevated p53 levels in colon tissue, suggesting GH may act as a tumor promoter by suppressing gene transcription of p53, PTEN, and APC levels ( FIGURE 2 Role of IGF1 Signaling in Cancers Numerous studies have demonstrated that IGF1 signaling is involved in tumor growth and is a prognostic factor for different cancer types (Papa et al., 1993

Reduced lipogenesis The same metabolic research reported AOD-9604 suppressing the formation of new fat alongside its lipolytic effect, which points to action on both sides of the fat-storage balance [1]

Compare this to tirzepatide, which can produce 22.5% total body weight loss over 72 weeks