The Mayo Clinic notes there is no solid proof that B12 shots produce weight loss on their own, so the realistic benefit comes from feeling well enough to move more and eat better
Furthermore, studies using a peripherally administered exenatide analogue conjugated to vitamin B12, which is sterically hindered from accessing regions protected by the blood brain barrier, improves glucose control in comparable fashion to unmodified exenatide, presumably at the level of the -cell, but does not induce emesis in the house musk shrew ( Suncus murinus) or rats (78, 79)
These medications help manage blood sugar levels and promote feelings of fullness to support weight loss
It is necessary for generating energy and forming red blood cells
Resistance training, sufficient protein, regular movement and appropriate medical supervision can help you achieve better-quality weight loss and remain physically capable throughout the process