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A marked difference in body weight gain is already apparent by day 8 (after the first week of METH operant intake): the short-access group gained over 20 grams, while the extended-access group increased by 10 grams, despite identical food intake

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One real-world study found nearly half of the people who used an earlier generation of GLP-1 medication for diabetes quit within a year and 70% within two years.Meanwhile, about 4% of people in a clinical trial stopped taking Wegovy because of side effects

Eli Lilly is targeting an FDA submission in late 2026