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If the out-of-pocket cost seems overwhelming, ask about manufacturer assistance, mail-order options, or a therapeutically appropriate on-formulary alternative

Last year, the Danish pharmaceutical giant Novo Nordisk doubled its sales of the diabetes drug in the country to almost $700m 5 percent of Ozempics global sales

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Topline results announced in December 2025 were positive, showing that orforglipron maintained weight loss after the switch

This evidence base extends to patients with high cholesterol because many of these trial participants had dyslipidemia as a baseline condition