Who Has a Higher Risk for Thrombosis While on GLP-1 Therapy Risk factors that raise the baseline chance of clotting include: Prior DVT or PE Known thrombophilia Active cancer Recent major surgery Prolonged immobilization Estrogen therapy Pregnancy Advanced age Tobacco use Severe dehydration and sudden immobility also raise clot risk during rapid weight change
The single-arm, open-label study enrolls 40 adults aged 1880 who have inadequate response to prior biologics, with participants receiving intravenous induction therapy every 4 weeks for 12 weeks followed by subcutaneous maintenance injections every 4 weeks for up to 2 years
Slower Gastric Emptying: By slowing the movement of food through the stomach, it enhances the feeling of fullness, reducing overall calorie consumption
One such investigation, known as the SUSTAIN-6 trial, was a moderate-sized trial that examined use of the once-weekly injectable agent semaglutide on cardiovascular outcomes when compared with placebo
Koska J, Sands M, Burciu C, D'Souza KM, Raravikar K, Liu J, Truran S, Franco DA, Schwartz EA, Schwenke DC