Several drugs, including colchicine, have been reported to reduce the absorption of methylcobalamin, vitamin B12
According to 2008 research, your body only absorbs about 1.3 percent of a 1,000 mcg oral dose and 2 percent of a 500 mcg oral dose
Efficacy in Treating B12 Deficiency: Methylcobalamin is a naturally occurring form of Vitamin B12, while Cyanocobalamin is a synthetic form
While it can vary from case to case, experts recommend taking oral vitamin B12 pills every day
Possible Side Effects Mild side effects of Vitamin B12 may include: ( 12 ) Mild pain, itching, or swelling at the injection site Temporary nausea or headache Mild diarrhea Hot flashes Vomiting These side effects do not affect all patients and are generally temporary and mild While rare, more serious side effects of Vitamin B12 injections can include ( 12 ): Irregular heartbeat Heart palpitations Hives or skin rash If you notice any severe reactions to a Vitamin B12 shot, contact a medical professional immediately