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Given the strong relationship between ROS and cell death, regulating ROS generation upward or controlling oxidative defense downward has become central for new cancer treatments, which have been enhanced by the finding that cancer cells process a higher level of ROS than do healthy cells (Galadari et al., 2017)
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doi: 10.1016/S0002-9440(10)64849-3 47 BurtonGJJauniauxE
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