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Caffeines ability to increase the production of PGE2 coupled with seizure induced PGE2 activation could potentially culminate to produce fatal outcomes when it occurs in the brainstem and may have occurred in our models

This bioavailability gap means oral dosing requires higher amounts to achieve equivalent systemic exposure

Angiogenesis, or new blood vessel formation, has been consistently observed in animal models, which improves nutrient delivery and accelerates healing in injured tissues

No matter how long it takes, having this reduced healing allows athletes to recover faster and, thus, get back to their sport or exercise quicker

While ALT is present only in cytoplasm, AST is present in both cytoplasm and mitochondria