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On the contrary, MC4R agonist, setmelanotide, was approved for the rare MC4R-deficiency, BardetBiedl syndrome (BBS), with severe obesity in childhood [10, 23]
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doi:10.5665/sleep.4732 Jordan AS, McSharry DG, Malhotra A
This reaction, catalyzed by the selenium-containing glutathione peroxidase, forms oxidized glutathione (G-S-S-G), which no longer has protective properties
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