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We found a pronounced inhibitory effect when opening K ATP -channels while stimulating with l-valine in the perfused rat small intestine, suggesting that changes in the membrane potential of GLP-1 secreting L-cells may play a crucial role in l-valine induced GLP-1 secretion
Complementing these findings, a separate trial assessing the efficacy of exenatide for alcohol use disorder also showed no significant difference in heavy drinking days overall
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Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
In contrast, intracerebroventricular injection, even at doses up to 300 ng, failed to influence acute or tonic flinching responses [24]
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