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Retatrutide activates GLP-1 receptors (insulin secretion, appetite suppression), GIP receptors (insulin secretion, adipose tissue modulation), and glucagon receptors (increased energy expenditure, hepatic glucose regulation) concurrently
Minimizes Weight Regain Risk : Since the process is steady, the results tend to be more stable
Longer satiety ensures meals are more filling
Separately, a meta-analysis in The American Journal of Geriatric Psychiatry found that individuals taking a GLP-1 showed significantly lower scores on a depression scale
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