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Current guidelines do not recommend this supplement for preventing CIPN (54)

Several studies have shown that obesity is an independent risk factor for the onset of CKD as well as its severity

Hypoglycemia is a recognized risk because IGF-1 has insulin-mimetic properties at the receptor level

Iron malabsorption can also be due to gastrointestinal disorders of autoimmune etiology (celiac disease, atrophic gastritis, IBD), which are often associated with autoimmune thyroid diseases [59, 60]

Supplementing may support the levels already present in the mothers system, though direct impacts on milk concentration are still being researched