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NEJM Evidence

Rigorous testing shows that these medications are stable when exposed to extreme temperatures exceeding 100F for short periods and at room temperature for several weeks

The Centers for Disease Control and Prevention ( CDC ) reports that nearly 50 percent of Americans attempt to lose weight each year, and the World Health Organization ( WHO ) says that complications from obesity or being overweight kill at least 2.8 million people yearly in what the organization calls a global epidemic

Back Deacon, DF, Johnsen, AH, Holst, JJ (March 1995) 'Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo', Journal Clinical Endocrinology Metabolism , 80/3, 952-7

This effect usually diminishes as your body adjusts to its new weight