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Proceedings of the National Academy of Sciences of the United States of America, 117 (47), 2995929967

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Somat Cell Mol Genet

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The disadvantage here is that one cannot distinguish between direct effects of the KO and side effects caused, for example, by different immune cell status or decreased caloric intake

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In addition, a substance which has not been approved for human use is likely to be prohibited as well

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It does not directly raise resting metabolic rate

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