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Chronic activation of the innate immune system associated with hyperglycaemia leads to persistent low-grade inflammation, which contributes to a range of complications, such as impaired cell function, insulin resistance and impaired glucose homeostasis, leading to the onset and progression of diabetes and its complications [1,2,3,4]
The specific NOX system of phagocytic cells is a multisubunit complex whose function is to generate reactive oxygen species (ROS) as a means to destroy invading pathogens
Antioxidants like vitamin C and glutathione help protect organs from damage
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