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To further substantiate the role of m 6 A mRNA degradation in PNT, we examined mRNA stability in Ythdf2 knockout conditions during PNT

The carnitine molecule formed is then shuttled back into the intermembrane space by the same cotransporter (CACT) while the fatty acyl-CoA enters -oxidation

doi: 10.1016/j.pediatrneurol.2020.09.009 83

Finally, we identify current research gaps and propose future directions toward harnessing AST for promoting cognitive resilience and delaying the progression of neurodegenerative disorders

These features make SLU-PP-332 a valuable chemical probe for dissecting ERR-dependent physiology in cells and intact animals