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Emerging evidence suggests that modulation of SCFA production may offer therapeutic avenues for neuroinflammatory and neurodegenerative conditions

Compounds targeting metabolic molecular targets Targeting glycolysis 2-deoxy-D-glucose (2-DG) is a well-known glycolysis inhibitor that specifically targets the activity of HK2 [256]

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The literature reports a higher concentration of inflammatory cytokines markers such as IL-2, IL-6, IL-15, TNF-, and IFN- and, in contrast, decreased anti-inflammatory cytokines like IL-4 and IL-10 (Lotti et al., 2015