glp-1 euglycemic dka Proposed mechanism of induced by SGLT2-inhibitors UNMASKING EUGLYCEMIC DKA IN TIRZEPATIDE

Higher Relative Risk for Osteomalacia: The same AAOS study indicated that while rare, the relative risk for osteomalacia (bone softening) was more than double in the GLP-1 group

Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial

4 As the numbers on the scale decrease, however, a common and valid question arises: "Am I losing muscle along with the fat?" It's important to understand that losing some muscle, or more accurately, lean body mass (which includes muscle, water, bone, and organs), is a typical aspect of weight loss, regardless of the method used

What Causes Post-Injection Flares A steroid flare happens when cortisone crystals form in the joint

Administration Injectable GLP-1 medications: Self-administered subcutaneous injection Small needle, minimal discomfort for most Common injection sites: abdomen, thigh, upper arm Rotate sites to prevent tissue irritation Most are once-weekly (semaglutide, tirzepatide, dulaglutide) Oral semaglutide (Rybelsus): Must be taken on empty stomach No more than 4 oz water Wait 30 minutes before eating or taking other medications Daily dosing Long-Term Considerations Understanding the long-term picture helps with treatment planning