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GLP-1 receptor agonists such as Ozempic, Zepbound, or Mounjaro are used to treat type 2 diabetes and obesity, however, they may also have positive effects on other health conditions

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Scientists now understand that beneficial bacteria help produce compounds called short-chain fatty acids (SCFAs), including butyrate, which play major roles in insulin sensitivity, satiety signaling, gut barrier integrity, and metabolic flexibility

Cell viability and proliferation assays The transfected K-562 cells with or without cell sorting and the negative control cells transfected with empty plasmids pcDNA3.1-GST DAF or pcDNA3.1-GST CEAM7 were counted and seeded into 96-well plates in triplicates at a density of 1,000 per well

However, several critical knowledge gaps persist in the current evidence base